Fig. 3From: Experimental cross-species infection of donkeys with equine hepacivirus and analysis of host immune signaturesAnalysis of deregulated genes. The threshold for deregulated genes (DREG) was set at a fold change above or below 2 or − 2, a significant p-value (FDR < = 0.05) and reads per kilobase million mapped reads (RPKM) of at least 1. A Number of up- and down-regulated genes per sample. Saturated area corresponds to immune-associated genes. B Overview of DREGs within each sample. Yellow dots indicate immune-associated genes. C Overlap of genes between the donkey and horse reference genome (upper Venn diagram). Overlap of all up- and down-regulated genes (indicated by arrows)Back to article page